Statistical analysis of dose heterogeneity in circulating blood: implications for sequential methods of total body irradiation.

Authors: Molloy JA
Improvements in delivery techniques for total body irradiation (TBI) using Tomotherapy and intensity modulated radiation therapy have been proven feasible. Despite the promise of improved dose conformality, the application of these “sequential” techniques has been hampered by concerns over dose heterogeneity to circulating blood. The present study was conducted to provide quantitative evidence regarding the potential clinical impact of this heterogeneity.
PMID: 21158268 [PubMed - in process] (Source: Medical Physics)

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