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A Randomized Controlled Trial of Exercise to Improve Mood After Traumatic Brain Injury

Posted on September 30th 2010
Objective: To test the hypothesis that a structured aerobic exercise regimen would decrease the severity of depressive symptoms in people with traumatic brain injury (TBI) who reported at least mild depression severity at baseline.Design: Prospective, randomized, controlled trial.Setting: Community gymnasium.Participants: Subjects with a history of a prior TBI (6 months to 5 years post-injury), recruited from the community. Inclusion criteria included scoring ≥5 on the Patient Health Questionnaire-9. Subjects were excluded if they were non-English speakers, had a medical condition precluding exercise, had suicidal ideation, regularly exercised, or could not use standard aerobic exercise equipment.Intervention: Weekly supervised exercise sessions over a 10-week period consisted of educati...

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