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Amantadine May Improve Consciousness Recovery After TBI

Major Finding: Patients had significantly faster functional recovery as measured by the Disability Rating Scale over 4 weeks of treatment with amantadine, compared with patients who received placebo (P = .007). (Source: Clinical Neurology News)

Comparison of Clinical Performance of Cranial Computed Tomography Rules in Patients With Minor Head Injury: A Multicenter Prospective Study

Conclusions:  For clinically important TBI, the three cranial CT decision rules had much lower sensitivities in this population than the original published studies, while the specificities were comparable to those studies. The sensitivities for neurosurgical intervention, however, were comparable to the original studies. The NEXUS‐II rule showed the highest reduction rate for CT scans compared to other rules, but failed to identify all undergoing neurosurgical intervention for their original inclusion cohort. (Source: Academic Emergency Medicine)

Amantadine May Improve Consciousness Recovery After TBI

Major Finding: Patients had significantly faster functional recovery as measured by the Disability Rating Scale over 4 weeks of treatment with amantadine, compared with patients who received placebo (P = .007). (Source: Clinical Neurology News)

Comparison of Clinical Performance of Cranial Computed Tomography Rules in Patients With Minor Head Injury: A Multicenter Prospective Study.

Conclusions:  For clinically important TBI, the three cranial CT decision rules had much lower sensitivities in this population than the original published studies, while the specificities were comparable to those studies. The sensitivities for neurosurgical intervention, however, were comparable to the original studies. The NEXUS-II rule showed the highest reduction rate for CT scans compared to other rules, but failed to identify all undergoing neurosurgical intervention for their original inclusion cohort. PMID: 21676057 [PubMed - as supplied by publisher] (Source: Accident and Emergency Nursing)

Comparison of Clinical Performance of Cranial Computed Tomography Rules in Patients With Minor Head Injury: A Multicenter Prospective Study

Conclusions:  For clinically important TBI, the three cranial CT decision rules had much lower sensitivities in this population than the original published studies, while the specificities were comparable to those studies. The sensitivities for neurosurgical intervention, however, were comparable to the original studies. The NEXUS‐II rule showed the highest reduction rate for CT scans compared to other rules, but failed to identify all undergoing neurosurgical intervention for their original inclusion cohort. (Source: Academic Emergency Medicine)
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