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Worse Outcomes With Decompressive Craniectomy After TBI

Although intracranial pressure and ICU stay were reduced, this strategy was associated with more unfavorable outcomes in patients with diffuse traumatic brain injury. Medscape Medical News (Source: Medscape Emergency Medicine Headlines)

Abbreviated Environmental Enrichment Enhances Neurobehavioral Recovery Comparably to Continuous Exposure After Traumatic Brain Injury

Conclusions. These data demonstrate that abbreviated EE (6 hours) produces motor and cognitive benefits similar to continuous EE after TBI and thus may be considered a dose-relevant rehabilitation paradigm. (Source: Neurorehabilitation and Neural Repair)

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Brain and Spinal Cord Interaction: A Dietary Curcumin Derivative Counteracts Locomotor and Cognitive Deficits After Brain Trauma

Conclusions. These studies define a mechanism by which TBI can compromise centers related to cognitive processing and locomotion. The findings also show the influence of the curcumin derivative on synaptic plasticity events in the brain and spinal cord and emphasize the therapeutic potential of this noninvasive dietary intervention for TBI. (Source: Neurorehabilitation and Neural Repair)

CSF Bcl-2 and cytochrome C temporal profiles in outcome prediction for adults with severe TBI

Authors: Amy K Wagner, Krutika B Amin, Christian Niyonkuru, Brett A Postal, Emily H McCullough, Haishin Ozawa, C Edward Dixon, Hulya Bayir, Robert S Clark, Patrick M Kochanek & Anthony Fabio (Source: Journal of Cerebral Blood Flow)

Evidence-Based Cognitive Rehabilitation: Updated Review of the Literature From 2003 Through 2008

Conclusions: There is substantial evidence to support interventions for attention, memory, social communication skills, executive function, and for comprehensive-holistic neuropsychologic rehabilitation after TBI. Evidence supports visuospatial rehabilitation after right hemisphere stroke, and interventions for aphasia and apraxia after left hemisphere stroke. Together with our prior reviews, we have evaluated a total of 370 interventions, including 65 class I or Ia studies. There is now sufficient information to support evidence-based protocols and implement empirically-supported treatments for cognitive disability after TBI and stroke. (Source: Archives of Physical Medicine and Rehabilitation)
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