Posted on February 28th 2011
Authors: Marvasti JA
Over 1.9 million U.S. veterans have been deployed to the Middle East since 2001. Statistics showthatwhentheyreturn, a significant number of them will develop psychiatric/psychosomatic disorders. Many of these returning veterans will be seen in primary-care offices or at hospitals. It is important for physicians to be familiar with combat trauma, post-traumatic stress disorder (PTSD), traumatic brain injury (TBI), and acute stress disorder (ASD). Best standard of care, pharmacological treatment of war trauma and its comorbidities-depression, suicide, aggression, addiction and other disorders are reviewed. As part of the treatment protocol, the author has also designed a 12-Step Self-Help Proposal for combat veterans with PTSD, inspired by addiction and AA self-help ...
Posted on February 28th 2011
Authors: Ishikawa F, Suzuki S, Okumiya A, Shimizu Y
Research on caregiving experiences of families of patients with traumatic brain injuries has been limited to studies emphasizing negative aspects of care. During this study, families caring for patients with traumatic brain injury (TBI) shared their experiences, allowing us to collect basic data about factors related to their psychosocial adjustment. Fifteen primary caregivers were interviewed using semistructured interviews, and content analysis was performed on obtained data. One thousand eighteen recording units were grouped into seven categories: (1) spending time with the patient with TBI and understanding invisible disabilities, (2) evaluating medical professionals' handling of the case, (3) devoting oneself to caring for the pa...
Posted on February 28th 2011
Authors: Bales JW, Yan HQ, Ma X, Li Y, Samarasinghe R, Dixon CE
Traumatic brain injury (TBI) causes persistent neurologic deficits. Current therapies, predominantly focused upon cortical and hippocampal cellular survival, have limited benefit on cognitive outcomes. Striatal damage is associated with deficits in executive function, learning, and memory. Dopamine and cAMP regulated phosphoprotein 32 (DARPP-32) is expressed within striatal medium spiny neurons and regulates striatal function. We found that controlled cortical impact injury in rats produces a chronic decrease in DARPP-32 phosphorylation at threonine-34 and an increase in protein phosphatase-1 activity. There is no effect of injury on threonine-75 phosphorylation or on DARPP-32 protein. Amantadine, shown to be efficacious i...
Posted on February 28th 2011
NAPLES, FLA. â About one-third of elderly patients who underwent a cranial operation for traumatic brain injury die in the hospital, and one-half are dead within a year, according to a retrospective analysis of 164 patients. (Source: Clinical Neurology News)
Posted on February 28th 2011
Major Finding: Mild traumatic brain injury is not independently associated with postdeployment psychosocial health problems such as depression or problematic drinking. (Source: Clinical Neurology News)
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